Rihanna

• Smurfette (voice)

James Corden

• No Name (voice)

Nick Offerman

• Ken (voice)

JP Karliak

• Gargamel / Razamel (voice)

Dan Levy

• Joel (voice)

Amy Sedaris

• Jaunty (voice)

Natasha Lyonne

• Mama Poot (voice)

Sandra Oh

• Moxie Smurf (voice)

Jimmy Kimmel

• Tardigrade (voice)

Octavia Spencer

• Asmodius (voice)

Nick Kroll

• Chernobog (voice)

Hannah Waddingham

• Jezebeth (voice)

Alex Winter

• Hefty Smurf (voice)

Maya Erskine

• Vanity Smurf (voice)

Billie Lourd

• Worry Smurf (voice)

Xolo Maridueña

• Brainy Smurf (voice)

Kurt Russell

• Ron (voice)

John Goodman

• Papa Smurf (voice)

Chris Miller

• Grouchy Smurf / Camouflage Smurf (voice)

Rachel Butera

• Azrael / List Maker Smurf (voice)

Conrad Vernon

• Butler (voice)

Tyler Peterson

• Bellhop (voice)

Marshmello

• Turtle (voice)

Chris Prynoski

• Quiet Smurf / Way Back There Smurf / Shark Taming Smurf (voice)

Spencer X

• Sound Effects Smurf (voice)

Hugo Miller

• Clumsy Smurf (voice)

Ryan Naylor

• Calendar Smurf (voice)

Jonny Manganello

• Baker Smurf (voice)

DJ Snake

• DJ Snake (voice)

Léa Elui

• Featured Paris Disco Dancer (voice)

Yuuki Luna

• Smurfette Anime (voice)

Daisuke Tsuji

• No Name Anime (voice)

Keisuke Hoashi

• Razamel Anime (voice)

Chris Miller

Rihanna

Ryan Harris

Jay Brown

Tyran "Ty Ty" Smith

Pam Brady

Peyo

Tom Myers

Coya Elliott

Randy Thom

Gary Rizzo

Henry Jackman

Rihanna

Matthew Landon

Pete Chiappetta

Andrew Lary

Anthony Tittanegro

Marco Furbatto

Margaret Wuller

Giulia De Stefano

Daniela Zorzetto

Arianna Palmucci

Peter Lyons Collister

Andrew Babick

Chris Kazmier

Danilo Bollettini

Gwyn Sannia

Rosario Pucciarelli

Edoardo Galeone

Flavia Battista

Maurizio Tiella

Peter Lyons Collister